Radhe (Salman Khan) is a hard-core gangster . A sharp-shooter with a sharp brain, he works for Gani Bhai, the dreaded Mafioso, on his own terms. Totally fearless, Radhe singlehandedly eliminates Gani Bhai's enemies, one by one - making more enemies in the process. The man is devoid of any principles; he is arrogant, ruthless and does not care about the emotions of other people.
Radhe's astounded when young and pretty Jhanvi (Ayesha Takia) professes her affection for him. Inspector Talpade's lustful eyes fall on Jahnavi. He doesn't know that Jahnavi has developed a soft spot for Radhe. Jahnavi is a very simple innocent and a naive girl and she believes that everything is good in the world and nothing is bad. After she meets Radhe she realizes that all her previous notions were wrong and life after that becomes a roller coaster ride for her. There is a transition in her character then.
Whether it's the Golden gang or Data Pawle's Gang, everybody wants the biggest piece of the lucrative cake that is Mumbai and the only way to get it is to eliminate whoever gets in the way. As Mumbai reels under bloody gang wars, Commissioner Ashraf Khan Vows to make the city crime-free and starts his campaign by arresting 200 criminals.